AstraZeneca’s target price upped to 8,870p by Liberum over oncology pipeline potential
The broker, which retains a 'buy' recommendation, said the pharma giant is expected to be “a long-term outperformer”
Company
AstraZeneca PLC
LON:AZN
AstraZeneca is one of the world's leading pharmaceutical companies, with a broad range of medicines designed to fight disease. AstraZeneca has over 67,000 empolyees and operates in over 100 countries with growing presence in important emerging markets.
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AstraZeneca stops chronic kidney disease treatment trial early after “overwhelming efficacy”
The pharma company also announced Imfinzi has been approved for small cell lung cancer in combination with chemotherapies
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Small cap movers: Genedrive skyrockets with coronavirus test production ramp-up
A look back at some of the more interesting stories from London's junior market this week
AstraZeneca posts negative results for late-stage bladder cancer treatment
The base drug for the treatment is being tested in conjunction with chemotherapy in patients with the same disease
AstraZeneca completes sale of hypertension drugs rights
The initial US$350mln payment may be followed by optional instalments of up to US$40mln based on sales
AstraZeneca sells rights for constipation drug to RedHill Biopharma
AstraZeneca will retain rights to sell Movantik in Europe, Canada and Israel
AstraZeneca revenues surge ahead but coronavirus clouds current year
Sales will be driven by cancer drugs Enhertu, Lynparza and selumetinib in various markets and anaemia treatment Roxadustat in China
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FTSE 100 closes lower as coronavirus fears and corporate updates hit equities
Britain's blue-chip index closed down nearly 43 points at 7,409. The FTSE 250, conversely, went higher, gaining over 116 points at 21,790
AstraZeneca and Royal Bank of Scotland on the cards for Valentine’s Day
The two FTSE 100 constituents are scheduled to release their final results
Can AstraZeneca, Barclays and RBS's numbers provide a shot in the arm?
Other updates on the coming week's agenda include Ocado, TUI, Babcock and Dunelm
AstraZeneca takes back autoimmune drug, sells rights to blood pressure treatments
The new arrangement will see Allergan still fund the development costs incurred by AstraZeneca
AstraZeneca's Imfinzi granted orphan status as liver cancer treatment
Imfinzi and tremelimumab are now 'orphan drugs', meaning their development becomes a matter of public policy because they cure a rare disease
Mixed picture for UK pharma as AstraZeneca ‘top pick’ at Credit Suisse while GlaxoSmithKline knocked by Barclays downgrade
Credit Suisse said AZN's “top-line growth and underlying margin potential” made it the top firm in their assessments
AstraZeneca earnings to be hit by US$100mln write-down after trial stops
An independent data monitoring committee recommended to stop phase III of the trial on Epanova, which is still marketed in the US for other treatments
AstraZeneca weighs in with a double dose of good news
It has received a fast-track review of a diabetes drug while gaining approval for a blood treatment in China
AstraZeneca and Merck’s Lynparza drug approved by US FDA for pancreatic cancer
“Lynparza is now the only approved targeted medicine in biomarker-selected patients with advanced pancreatic cancer," said AstraZeneca's Dave Fredrickson.
AstraZeneca and Daiichi Sankyo's breast cancer treatment gets US approval
AstraZeneca and Daiichi Sankyo are exploring the further potential of Enhertu in HER2-breast cancer with three ongoing Phase III trials
AstraZeneca sells rights to breast, prostate cancer drugs for US$181mln
The FTSE 100-listed firm already sold commercial rights in the US in 2017, while now the drugs have lost exclusive rights in most countries in Europe and Africa
AstraZeneca’s presence in China boosted by Lynparza approval for ovarian cancer
Analysts said the prevalence of the BRCA-mutated ovarian cancer is higher in China and the approval will boost AstraZeneca’s already strong performance in the region
Addition by subtraction: AstraZeneca continues to slim down
It is selling the North American rights to its anti-psychotic products Seroquel and Seroquel XR. This is part of the Anglo-Swedish giant's focus on its core R&D portfolio and bunch blockbusters it owns
AstraZeneca cancer drug fast-tracked by the FDA
AZ wants to offer Imfinzi to people with late-stage small cell lung cancer
AstraZeneca's near-£100bn valuation is a vindication for Pascal Soriot
Since the Frenchman took the helm in October 2012, the drug giant's share price has increased by over 160%
AstraZeneca’s type-2 diabetes drug gets EU approval
Qtrilment, already approved in the US, comes in tablets and helps adults to control the level of sugar in the blood
AstraZeneca gets priority review in US for new NF1 treatment
The application is for the use of selumetinib in children aged three years and older.
AstraZeneca and the art of resurrecting failed drug candidates
Mereo and Evgen's drugs both stumbled as phase 2 trials yielded disappointing results, but an AstraZeneca-style turnaround could be around the corner
AstraZeneca’s lupus drug makes up for last year’s failure, faces competition
The FTSE 100-listed company said 47.8% of patients in phase III achieved a reduction of symptoms compared to 31.5% of those who used placebo
AstraZeneca anaemia drug data points to “yet another blockbuster”
Roxadustat could generate US$5bn in annual revenues, according to Shore Capital analysts
AstraZeneca to release data likely to move anaemia drug’s sales value by US$3.7bn, analysts say
Consensus is at US$1.3bn, although Shore Capital sees potential for up to US$5bn revenues if the US authorities do not deem necessary to include heart condition risks on the drug’s label
AstraZeneca to add $13bn product sales in next 5 years, says broker Liberum
Patent expiries have slowed Astra’s sales over the last few years, which retreated to $21bn in 2017, down from a peak of $34bn six years earlier
AstraZeneca hikes sales target after new drug successes
Product sales grew 16% in the third quarter, up from 12% in the first half of the year
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FTSE 100 closes higher, bolstered by Aveva and AstraZeneca; Boris Johnson to seek December general election
The blue-chip benchmark finished ahead by 67.51 points at 7,328.25 on the day
AstraZeneca likely to remain in favour, banks update on PPI
Prudential completes its M&G demerger on Monday, with the week also seeing WPP and Travis Perkins follow recent profit warnings from rivals and Reckitt Benckiser's new CEO makes his debut
FDA grants “priority review” status to AstraZeneca’s breast cancer antibody
“Trastuzumab deruxtecan has the potential to transform the treatment landscape for patients with HER2-positive metastatic breast cancer"
AstraZeneca gets US clearance for asthma pen
Fasenra sales surged 244% in its latest quarter to US$296mln as it became the preferred novel-biologic medicine for the treatment of severe asthma.
IPO Roundup: Several biotech companies set to go public this week; WeWork cancels its IPO filing
ADC Therapeutics, a Swiss biotech, expects to lead the pack with a $200 million offering
Glaxo and AstraZeneca vie for position with "unprecedented" ovarian cancer trials
Both pharma companies' PARP inhibitor drugs reduced disease progression and death by up to 40% in clinical trials
AstraZeneca shares hit all-time highs as it adds colour to recent trial data
Top-line data earlier this year only revealed that the drugs in those studies achieved “statistically significant” results, but Astra has now been able to quantify their effects
AstraZeneca scores another late-stage win, this time with COPD drug
Breztri Aerosphere, even when taken in smaller doses, was shown to be much more effective in reducing the number of exacerbations suffered by COPD patients than current drugs
Amryt Pharma: The AIM drug developer potentially sitting on a US$100mln piece of paper
Amryt has a chance of being awarded a priority review voucher, which sell for several times more than the company’s current market cap
AstraZeneca scores another regulatory win in China for roxadustat anaemia drug
Astra will now be able to treat all Chinese patients living with chronic kidney disease who experience anaemia, regardless of whether they require dialysis
AstraZeneca’s cancer drug combo stumbles in phase III lung cancer trial
Astra had been hoping to show that the combination of Imfinzi and tremelimumab was more effective in treating certain lung cancer patients than chemo
AstraZeneca nears £100bn market cap as remarkable drug pipeline turnaround continues
Only five years ago, AstraZeneca’s Symbicort inhaler generated more sales than all of the firm’s cancer drugs combined. The same can’t be said any more…
AstraZeneca pumps higher as Farxiga shows benefit in late-stage heart-failure study
Farxiga, when combined with current standard of care, was able to reduce the risk of cardiovascular death and the worsening of heart failure
AstraZeneca’s Lynparza meets primary endpoint in late-stage ovarian cancer trial
AstraZeneca is competing with GSK to win the race to become the go-to maintenance treatment for people who have been treated for ovarian cancer
AstraZeneca’s market value swells by £4bn after forecast-busting second-quarter results
Revenue beat forecasts by 5%, while operating profit was particularly impressive, coming in some 17% ahead of expectations
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FTSE 100 closes in red Thursday as ECB update underwhelms
There were mixed messages in Mario Draghi's update on Thursday
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Day ahead preview: Unilever, National Express, Diageo, ECB
With a slew of corporate earnings and the European Central Bank's policy decision, Thursday will be a busy day of news
GSK names former AstraZeneca finance boss as new chairman
Jonathan Symonds will be the man tasked with overseeing the mega merger of GSK and Pfizer’s consumer healthcare businesses
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ITV investors hope for Love Island boost amid tough ad market
The week ahead includes updates from ITV, Unilever, Rightmove, Diageo, Marston's, IG Group, National Express, GSK and AstraZeneca
GlaxoSmithKline edges higher as Zejula passes late-stage ovarian cancer study with flying colours
Zejula demonstrated a “statistically significant” improvement in progression free survival – the length of time a patient lives with the disease but it doesn’t get worse
US regulators grant orphan drug status to AstraZeneca’s Imfinzi cancer drug
Imfinzi recently showed in a late-stage study that, when combined with chemotherapy, it had a “clinically meaningful” effect on overall survival
AstraZeneca gets two positive opinions from European Medicines Agency committee
The Committee for Medicinal Products for Human Use (CHMP) recommended that diabetes medicine Forxiga should have its marketing authorisation updated to include cardiovascular data from recent clinical trials
AstraZeneca gets EU approval for Lynparza as ovarian cancer treatment
Pharma giant had been targeting annual peak sales of $2bn for the drug, of which $400mln was from ovarian cancer
AstraZeneca sees further encouraging effects from leukaemia treatment Calquence
Interim analysis of a phase III clinical trial has revealed that after 12 months, 88% of people saw no progression of the disease if they were given the drug
AstraZeneca drug for chronic lymphocytic leukaemia successfully navigates phase III trial
The results will “serve as the foundation for regulatory submissions later this year", said AZ’s vice president of oncology, José Baselga
AstraZeneca reports positive results from trial of pancreatic cancer treatment
Results from the trial of Lynparza showed “statistically significant and clinically meaningful improvement” in the time patients could live without their disease getting worse
Immuno-oncology: All you wanted to know but were too afraid to ask
Essentially, immuno-oncology involves developing drugs that use the body’s own immune system to fight cancers
Is London's fickle funding appetite part of Lasker's 'disastrous' cycle?
Stock market sage Bernard Lasker once said: “I can feel it coming...A whole new round of disastrous speculation, with all the familiar stages in order: blue-chip boom, then a fad for secondary issues, then an over-the-counter play, then a g
BHP, AstraZeneca and Shell among world’s top divi payers as shareholders gear up for record year of returns
Asset Manager Janus Henderson is predicting that global dividend pay-outs will reach almost US$1.5trn in 2019
Pharma stocks head south as Trump forces them to display drug prices in TV ads
“Drug companies have to come clean about their prices in TV ads. If drug companies are ashamed of those prices – lower them!”
AstraZeneca gets US regulatory green light for slow-release diabetes drug
Qternmet XR will be prescribed alongside diet and exercise advice to people to improve glycaemic control
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Loungers sees good start to first day of trading on AIM
A look at some of the biggest risers and fallers in London on Monday
AstraZeneca first-quarter profits double as product sales revival continues but cash still a worry
The oncology portfolio has helped to turn around Astra’s product sales, which for years had been falling as key drugs went off-patent
Investments and investor services
FTSE 100 closes just in red as crude price decline hits resource stocks
The UK blue-chip index finished down nearly six points at 7,428 on Friday
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City set for unusually busy Friday with RBS leading the way
Alongside RBS, AstraZeneca, Just Eat, WPP and Pearson are all due to publish first-quarter trading updates on Friday
Investments and investor services
FTSE 100 closes at near seven month high as no news is deemed good news
The UK blue-chip index finished up around 63 points at 7,523
While UK dividends hit record £19.7bn in first quarter, some FTSE 100 companies could be headed for cuts
Basic measures like dividend cover suggest a number of blue chips might be struggling to maintain their payouts at current levels
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Once Easter is over, a plethora of blue-chip big guns are set to report trading updates and results
The Week Ahead will bring updates from the likes of Royal Bank of Scotland and Barclays, plus drugs giant AstraZeneca, and media groups WPP, Pearson and WPP
AstraZeneca’s new Japanese cancer drug tipped to rack up billions in annual sales
Liberum thinks trastuzumab deruxtecan can generate peak sales of more than US$3bn, given the drug’s potential in a host of cancer indications
AstraZeneca is still not converting top-line momentum into cash-flow, says UBS
Astra has affected a “momentous turnaround” in sales growth, but it has struggled to turn that top-line momentum into cash flow, according to UBS
AstraZeneca granted Breakthrough Therapy Designation for rare genetic condition treatment
A breakthrough therapy designation is designed to expedite the development and review of medicines that are intended to treat a serious condition and have shown promise in early-stage clinical trials
Circassia gets a double shot in the arm from US regulators
Two of its COPD drugs, Tudorza and Duaklir, have been given the thumbs-up from US regulators
AstraZeneca launches UK's biggest cash call this year to fund £5.2bn Japanese cancer deal
The £2.7bn share placing will be used to make an upfront payment to Daiichi Sankyo, which has developed a potentially breakthrough new treatment for breast cancer
Investments and investor services
FTSE 100 closes in positive territory as MPs vote down May's deal again
Footsie closed at 7,279, up nearly 45 points on the day
AstraZeneca wins regulatory approval for Europe's first type-1 diabetes drug taken by mouth
“We look forward to bringing Forxiga to a patient population that has not had any approved oral medicines available before," said Elisabeth Björk, AZ’s head of cardiovascular, renal and metabolism
Investments and investor services
FTSE 100 closes higher as Bercow deals blow to May's Brexit plan
Bercow says the government can only bring back the vote if there has been substantial 'change' to the Brexit deal
FTSE 100 closes lower as Chinese data dents sentiment
The UK's premier share index closed down around 32 points at 7,074
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IAG, Rolls Royce and British American Tobacco on the agenda for busy blue chip Thursday
Its set to be a busy day for blue-chip news in London on Thursday.
AstraZeneca reports pancreatic cancer trial success for Lynparza
Lynparza though showed significantly increased rates of survival in the phase III POLO trial
AstraZeneca rises as Brilinta medicine meets goal in Phase III clinical trial
The company said during the trial Brilinta, when taken in conjunction with aspirin, had shown “a statistically-significant reduction” in major adverse cardiovascular events, such as heart attacks or strokes, compared to taking aspirin alone
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Hotchpotch of blue-chip results set to flow in coming week from likes of Rolls-Royce, ITV, WPP
The Week Ahead will also bring a trading update from AB Foods, plus final results from Standard Chartered, IAG, Persimmon, Rightmove, as well as the latest US GDP data
AstraZeneca posts first rise in annual product sales for almost ten years
Patent expiries on key blockbusters such as Crestor and Seroquel have put a huge dent in sales over the past decade or so, but Astra returned to growth in 2018
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FTSE 100 closes a tad higher but sentiment dented by US data
FTSE 100 closed up just over six points at 7,197, while FTSE 250 shed over 74 at 18,898
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Drug firms AstraZeneca and Indivior to be in spotlight on Thursday
AstraZeneca, Indivior and Coca-Cola HBC are among the higher profile names in the schedule for Thursday.
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FTSE 100 closes higher as investors buoyed by trade talk optimism
The UK's premier share index added almost 58 points at 7,129, while the FTSE 250 also gained ground
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Blue-chip corporate update mill to continue to grind, with RBS and AstraZenca to the fore
Aside from all the company news, the Week Ahead also brings the latest UK inflation and GDP growth data for investors to digest, while the Brexit saga will continue to roll on
Double boost from European and US regulators for AstraZeneca’s lung infection treatment
MEDI8897 is being developed as a treatment for a respiratory syncytial virus – a major cause of lower respiratory tract infection which affects around 90% of children under two
Lloyds added to JPMorgan Cazenove’s European Best Equity Ideas Overweight List
JPMorgan's European Best Equity Ideas list summarises the bank’s EMEA Equity research team’s views and top picks, covering both strategy and sector contributions
AstraZeneca appoints leading cancer researcher José Baselga as new head of oncology R&D
Baselga resigned from his position as physician-in-chief at Memorial Sloan Kettering Cancer Center last year amid reports that he had failed to disclose payments from healthcare companies in some of his research articles
Biotech CEOs gather in San Francisco to mull 2019 outlook
On the agenda at this year's Biotech Showcase is a panel discussion entitled “Cell and gene therapy: The financing surge” featuring Orgenesis CEO Vered Caplan
Investments and investor services
FTSE 100: The good, the BATS and the Ocado in 2018
For Ocado, it was a case of "eat my shorts" as short sellers got burnt while for BATS, not enough cigarettes got burnt as e-cigarettes rose in popularity
Hat-trick for AstraZeneca as its cancer and anaemia drugs come up trumps in three late-stage trials
Lynparza improved response rates in a subset of ovarian cancer patients, while Roxadustat boosted haemoglobin count in people with anaemia
GlaxoSmithKline shares drift lower as Morgan Stanley reinitiates coverage with ‘underweight’ stance
The US investment bank set a price target of 1,460p on the FTSE 100-listed firm, with Glaxo's shares trading at 1,476.20p late morning, down 0.4% on Thursday’s closing price
Sterling slump: Who’s benefitting?
On Monday, fresh Brexit volatility pushed the pound to a yearly low against the dollar but despite the turmoil, some firms are profiting handsomely
AstraZeneca’s Imfinzi cancer drug fails in another late-stage trial
The drug failed to prolong the lives of patients with advanced head and neck cancers when it was used alone or in combination with another treatment, in comparison to standard chemo
Barclays downgrades GSK; warns of “significant EPS dilution” from Tesaro acquisition
Barclays reckons the GSK valuation remains appealing, but is waiting until 2019 before piling back in, as it thinks the shares might drift a little lower yet
AstraZeneca in cancer drug setback
The phase III trial involved patients with very late stage lung cancer where the disease had spread to other organs - in other words, the group was hard to treat
Investments and investor services
FTSE 100 closes Friday in the red after tumultuous week for UK politics
The UK's premier share index lost around 24 points at 7,013 on the day - and was down 1.29% on the week.
AstraZeneca sells off US rights to children’s lung disease treatment for up to US$2bn
Over the past couple of weeks, the FTSE 100 drugs giant has sold off the rights to three asthma and hay fever treatments, one heartburn medicine, an arthritis drug and now a lung disease treatment
AstraZeneca serves up a double dose of good news
It said the US regulator had granted a priority review for its new cancer treatment and told investors a phase III trial of its diabetes medication delivered impressive results